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BriefROBOTICS

Micro Targeted Drug Delivery Robot Swarm NanoCourier FDA-Approved: Nanoscale Robots Precisely Deliver Chemotherapy to Tumor Interior

Caltech spinoff NanoMed launches magnetically driven micro drug delivery robot swarm NanoCourier, with 500nm diameter robot clusters guided by external magnetic fields to precisely reach tumor interiors, reducing systemic side effects by 95%.

Caltech spinoff NanoMed today announced FDA approval for its magnetically driven micro drug delivery robot swarm NanoCourier. NanoCourier consists of billions of 500nm magnetic nanoparticles — each robot is essentially a magnetic nanoparticle包裹着chemotherapy drug with tumor-targeting antibodies on its surface.

After administration, NanoCourier clusters navigate the body guided by external magnetic fields, accumulating at tumor sites. When the magnetic field applies specific alternating frequencies, nanoparticle surface temperature rises slightly, triggering drug release. The entire process achieves precise control over "where to release and how much."

In liver cancer clinical trials, NanoCourier increased chemotherapy drug concentration at tumor sites by 20x while reducing systemic side effects (hair loss, nausea, white blood cell reduction) by 95%.