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Deep diveTECH

Neuromorphic Olfactory Sensor NoseChip Deep Dive: Machines Achieve Human-Comparable Odor Recognition for the First Time

NoseChip, developed jointly by Caltech and Bosch, mimics the human olfactory nervous system's signal processing approach, achieving 98.7% accuracy in identifying 2,000 odors — surpassing trained perfumers.

Neuromorphic Olfactory Sensor NoseChip Deep Dive: Machines Achieve Human-Comparable Odor Recognition for the First Time

The neuromorphic olfactory sensor NoseChip, jointly developed by Caltech's Neuroengineering Laboratory and Bosch, was published in Science on August 23, 2030. The sensor mimics the signal processing mechanism of the human olfactory nervous system, achieving 98.7% accuracy in identifying 2,000 common odors — the first time machine olfaction has reached or surpassed human levels.

NoseChip's core innovation lies in "spiking olfactory encoding." Traditional electronic noses use metal oxide sensor arrays that output analog voltage signals requiring complex pattern recognition algorithms for post-processing. NoseChip directly converts chemical sensing into neuromorphic spike sequences, where the time intervals and frequencies of each spike encode the chemical characteristics of odor molecules.

The sensor array consists of 4,096 nanowire sensing units, each surface-modified with different odor-binding proteins (OBPs) derived from fruit fly olfactory receptors. When odor molecules bind to OBPs, the nanowire's conductivity changes, triggering spike signals.

Caltech Professor Wei Chen explained: "The human olfactory system doesn't simply detect chemicals — it converts chemical information into neural signals through spike encoding. NoseChip is the first to reproduce this process on a silicon chip."

In comparative tests with professional perfumers, NoseChip outperformed human experts in distinguishing similar odors (such as different varieties of rose essential oil). Bosch's VP of Sensor Technology said: "NoseChip's application prospects include food safety testing, environmental monitoring, medical diagnostics (detecting diseases through breath analysis), and smart homes."

The research team plans to launch a consumer-grade NoseChip module in 2031, targeting a price under $50, which can be integrated into smartphones and wearable devices.